Tekkon Kinkreet

From Viz:
Orphaned on the mean streets of Treasure Town, lost boys Black and White must mug, steal and fight to survive. Around them moves a world of corruption and loneliness, small-time crooks and neurotic police officers, and a band of sadistic yakuza who have plans for their once-fair city. Can they rise above their environment?
Won the Best U.S. Edition of International Material – Japan for the Eisner Award in 2008.